In recent years, a technique of computer prosthesis milling (CAD/CAM technology – computer aided design/computer aided manufacturing) is used more and more widely in restorative surgery along with traditional prosthesis manufacturing by the “silicone key” method. Growth of popularity of this technique is explained by a number of factors: high accuracy, aesthetics, and comparative quickness of prosthesis manufacturing (in some cases, during a single visit and by a dentist’s chair). Research has shown that, when the CAD/CAM technology is used and manufacturers’ recommendations are considered (prostheses should be manufactured of industrial ceramic blocks), fixed bridge prostheses made of Luxatemp AM plus, Trim, and Cercon Base PMMA materials have higher mechanical strength than those manufactured by the traditional “silicone key” method of the same materials though the cost of the former prostheses appears higher than the cost of the latter ones. The question is: is it possible to combine high accuracy and quickness of prosthesis manufacturing under the CAD/CAM technology and a laboratory method of manufacturing of blocks for milling? And if yes, will prostheses produced in such a way be strong enough? All these questions are discussed in the article. Research has been conducted with regard to static and fatigue bending strength of temporary fixed bridge prostheses manufactured of certain provisional materials (Protemp, Luxatemp, Sinma) and comparison has been carried out with regard to strength of prostheses manufactured of the Sinma material according to the traditional technology and by the method of computer milling. The research has been conducted jointly by Institute of Mechanics of the Moscow Lomonosov State University (MGU) and the “General stomatology and training of dental technicians” department of the Moscow State Medical Stomatological University.